ABSTRACT
Gestational trophoblastic tumor associated with ectopic pregnancy is a very rare event. This paper reports a case of an invasive mole arising from a tubal pregnancy. Patient is a 26-year-old G2L1Ep1 who was referred to Isfahan Beheshti Hospital due to rise in BHCG level after surgery of ectopic pregnancy [EP]. The patient had initially been treated with salpingectomy. The pathologic study of specimen was invasive mole. The patient underwent two period of MTX treatment. Because of sonographic report of adnexal mass, the patient underwent laparotomy. The result of laparotomy was invasive mole. The patient underwent EMACO regimen and was released when the BHCG was 1. Appropriate monitoring of BHCG titers following surgery of EP is important not only to diagnose persistent EP, but also for rejecting the presence of GTT. In addition, follow up of the pathologic report is also important, although the clinical diagnose seems to be correct